Detection of a novel astrovirus from a black-naped monarch (Hypothymis azurea) in Cambodia

Virol J. 2015 Nov 4:12:182. doi: 10.1186/s12985-015-0413-2.

Abstract

Background: Astroviruses are comprised of two genera with Avastrovirus infecting birds and Mamastrovirus infecting mammals. Avastroviruses have primarily been associated with infections of poultry, especially chicken, turkey, duck, and guineafowl production systems, but also infect wading birds and doves. Outcomes result in a spectrum of disease, ranging from asymptomatic shedding to gastroenteritis with diarrhea, stunting, failure to thrive and death.

Findings: Virological surveillance was conducted in birds from two sites in Cambodia in 2010. Samples were screened for influenza, astroviruses, coronaviruses, flaviviruses, and paramyxoviruses. A total of 199 birds were tested and an astrovirus was detected in a black-naped monarch (Hypothymis azurea).

Conclusions: This is the first astrovirus detection in a passerine bird. Phylogenetic analysis and nucleotide distances suggest that this avastrovirus forms a distinct lineage and may constitute a fourth avastrovirus group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Astroviridae Infections / veterinary*
  • Astroviridae Infections / virology
  • Avastrovirus / classification*
  • Avastrovirus / isolation & purification*
  • Bird Diseases / virology*
  • Cambodia
  • Cluster Analysis
  • Molecular Sequence Data
  • Passeriformes / virology*
  • Phylogeny
  • Polymerase Chain Reaction
  • RNA, Viral / genetics
  • Sequence Analysis, DNA
  • Sequence Homology

Substances

  • RNA, Viral