Central Nervous System Cancers, Version 1.2015

Louis Burt Nabors; Jana Portnow; Mario Ammirati; Joachim Baehring; Henry Brem; Paul Brown; Nicholas Butowski; Marc C Chamberlain; Robert A Fenstermaker; Allan Friedman; Mark R Gilbert; Jona Hattangadi-Gluth; Matthias Holdhoff; Larry Junck; Thomas Kaley; Ronald Lawson; Jay S Loeffler; Mary P Lovely; Paul L Moots; Maciej M Mrugala; Herbert B Newton; Ian Parney; Jeffrey J Raizer; Lawrence Recht; Nicole Shonka; Dennis C Shrieve; Allen K Sills Jr; Lode J Swinnen; David Tran; Nam Tran; Frank D Vrionis; Stephanie Weiss; Patrick Yung Wen; Nicole McMillian; Anita M Engh

doi:10.6004/jnccn.2015.0148

Central Nervous System Cancers, Version 1.2015

J Natl Compr Canc Netw. 2015 Oct;13(10):1191-202. doi: 10.6004/jnccn.2015.0148.

Authors

Louis Burt Nabors¹, Jana Portnow¹, Mario Ammirati¹, Joachim Baehring¹, Henry Brem¹, Paul Brown¹, Nicholas Butowski¹, Marc C Chamberlain¹, Robert A Fenstermaker¹, Allan Friedman¹, Mark R Gilbert¹, Jona Hattangadi-Gluth¹, Matthias Holdhoff¹, Larry Junck¹, Thomas Kaley¹, Ronald Lawson¹, Jay S Loeffler¹, Mary P Lovely¹, Paul L Moots¹, Maciej M Mrugala¹, Herbert B Newton¹, Ian Parney¹, Jeffrey J Raizer¹, Lawrence Recht¹, Nicole Shonka¹, Dennis C Shrieve¹, Allen K Sills Jr¹, Lode J Swinnen¹, David Tran¹, Nam Tran¹, Frank D Vrionis¹, Stephanie Weiss¹, Patrick Yung Wen¹, Nicole McMillian¹, Anita M Engh¹

Affiliation

¹ From University of Alabama at Birmingham Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; Yale Cancer Center/Smilow Cancer Hospital; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The University of Texas MD Anderson Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of Washington/Seattle Cancer Care Alliance; Roswell Park Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; University of Michigan Comprehensive Cancer Center; Memorial Sloan Kettering Cancer Center; St. Jude Children's Research Hospital/University of Tennessee Health Science Center; Massachusetts General Hospital Cancer Center; American Brain Tumor Association; Vanderbilt-Ingram Cancer Center; Mayo Clinic Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Cancer Institute; Fred & Pamela Buffet Cancer Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Moffitt Cancer Center; Fox Chase Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; National Comprehensive Cancer Network.

PMID: 26483059
DOI: 10.6004/jnccn.2015.0148

Abstract

The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Central Nervous System (CNS) Cancers provide interdisciplinary recommendations for managing adult CNS cancers. Primary and metastatic brain tumors are a heterogeneous group of neoplasms with varied outcomes and management strategies. These NCCN Guidelines Insights summarize the NCCN CNS Cancers Panel's discussion and highlight notable changes in the 2015 update. This article outlines the data and provides insight into panel decisions regarding adjuvant radiation and chemotherapy treatment options for high-risk newly diagnosed low-grade gliomas and glioblastomas. Additionally, it describes the panel's assessment of new data and the ongoing debate regarding the use of alternating electric field therapy for high-grade gliomas.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Central Nervous System Neoplasms / drug therapy*
Central Nervous System Neoplasms / pathology
Central Nervous System Neoplasms / radiotherapy*
Humans
Neoplasm Metastasis
Practice Guidelines as Topic*