In Vitro Antibiotic Susceptibility of Initial Pseudomonas aeruginosa Isolates From United States Cystic Fibrosis Patients

J Pediatric Infect Dis Soc. 2015 Jun;4(2):151-4. doi: 10.1093/jpids/pit052. Epub 2013 Sep 10.

Abstract

Chronic antibiotic suppression of cystic fibrosis (CF) infections has increased in the United States, as has isolation of Pseudomonas aeruginosa with reduced antibiotic susceptibility. However, analysis of the susceptibilities of 193 initial P aeruginosa clinical isolates suggests that antibiotic susceptibilities are comparable with wild-type strains despite expanded antipseudomonal treatment in the CF community.

Keywords: cystic fibrosis; initial P aeruginosa; susceptibility.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Child
  • Child, Preschool
  • Cystic Fibrosis / complications
  • Drug Resistance, Multiple, Bacterial / physiology*
  • Humans
  • Infant
  • Microbial Sensitivity Tests
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / microbiology*
  • Pseudomonas Infections / transmission
  • Pseudomonas aeruginosa / drug effects*
  • Pseudomonas aeruginosa / isolation & purification
  • United States

Substances

  • Anti-Bacterial Agents