Abstract
We report characterization of a methicillin-susceptible, vancomycin-resistant bloodstream isolate of Staphylococcus aureus recovered from a patient in Brazil. Emergence of vancomycin resistance in methicillin-susceptible S. aureus would indicate that this resistance trait might be poised to disseminate more rapidly among S. aureus and represents a major public health threat.
Keywords:
Brazil; MSSA; Staphylococcus aureus; antimicrobial resistance; bacteremia; bacteria; bacterial infections; gram-positive bacterial infections; methicillin susceptibility; methicillin-susceptible; methicillin-susceptible S. aureus; vancomycin resistance; vancomycin-resistant.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Bacteremia / drug therapy*
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Bacteremia / microbiology
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Brazil / epidemiology
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Humans
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Methicillin / pharmacology
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Methicillin / therapeutic use
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Microbial Sensitivity Tests / statistics & numerical data*
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Staphylococcal Infections / drug therapy*
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Staphylococcal Infections / epidemiology
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / isolation & purification
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Vancomycin / pharmacology*
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Vancomycin / therapeutic use
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Vancomycin Resistance / immunology
Substances
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Anti-Bacterial Agents
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Vancomycin
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Methicillin