YAP activates the Hippo pathway in a negative feedback loop

Cell Res. 2015 Oct;25(10):1175-8. doi: 10.1038/cr.2015.101. Epub 2015 Aug 28.

Authors

Xiaoming Dai¹, Huan Liu¹, Shuying Shen^{1

2}, Xiaocan Guo¹, Huan Yan¹, Xinyan Ji¹, Li Li³, Jun Huang¹, Xin-Hua Feng¹, Bin Zhao¹

Affiliations

¹ Life Sciences Institute and Innovation Center for Cell Signaling Network, Hangzhou, Zhejiang 310058, China.
² Institute of Biochemistry, College of Life Science, Hangzhou, Zhejiang 310058, China.
³ Institute of Aging Research, Hangzhou Normal University, Hangzhou, Zhejiang 311121, China.

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adaptor Proteins, Signal Transducing / genetics
Adaptor Proteins, Signal Transducing / metabolism*
Animals
Carcinogenesis / genetics
Carcinogenesis / metabolism
Cell Line
Cell Line, Tumor
Hippo Signaling Pathway
Humans
Mutation
Neoplasms / genetics
Neoplasms / metabolism
Phosphoproteins / genetics
Phosphoproteins / metabolism*
Phosphorylation
Protein Serine-Threonine Kinases / metabolism*
Signal Transduction*
Transcription Factors
YAP-Signaling Proteins

Substances

Adaptor Proteins, Signal Transducing
Phosphoproteins
Transcription Factors
YAP-Signaling Proteins
YAP1 protein, human
LATS1 protein, human
Protein Serine-Threonine Kinases