Neurocognitive Effects of Obesity and Bariatric Surgery

Eur Eat Disord Rev. 2015 Nov;23(6):488-95. doi: 10.1002/erv.2393. Epub 2015 Aug 19.

Abstract

This review paper will discuss the recent literature examining the relationship between obesity and neurocognitive outcomes, with a particular focus on cognitive changes after bariatric surgery. Obesity is now recognized as an independent risk factor for adverse neurocognitive outcomes, and severely obese persons appear to be at even greater risk. Bariatric surgery is associated with rapid improvements in cognitive function that persist for at least several years, although the mechanisms underlying these improvements are incompletely understood. Assessment of cognitive impairment in bariatric surgery patients is challenging, and improved methods are needed, as poorer performance on neuropsychological tests of memory and executive function leads to poorer clinical weight outcomes. In addition to its clinical importance, further study in this area will provide key insight into obesity-related cognitive dysfunction and clarify the possibility of an obesity paradox for neurological outcomes.

Keywords: BMI; bariatric; cognition; obesity.

Publication types

  • Review

MeSH terms

  • Bariatric Surgery*
  • Cognition / physiology*
  • Cognition Disorders / epidemiology*
  • Humans
  • Neuropsychological Tests
  • Obesity / physiopathology*
  • Obesity / surgery*
  • Risk Factors
  • Treatment Outcome