Sinonasal carcinoma presenting as chronic sinusitis and sequential bilateral visual loss

Indian J Ophthalmol. 2015 Jun;63(6):528-31. doi: 10.4103/0301-4738.162606.

Abstract

Sinonasal undifferentiated carcinoma-related rhinogenic optic neuropathy is rare and may lead to visual loss. To the best of our knowledge, this is the first report of bilateral sequential visual loss induced by this etiology. It is important to differentiate between chronic sinusitis and malignancy on the basis of specific findings on magnetic resonance images. Surgical decompression with multidisciplinary therapy, including steroids, chemotherapy, and radiotherapy, is indicated. However, no visual improvement was noted in this case, emphasizing the rapid disease progression and importance of early diagnosis and treatment.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Carcinoma / complications
  • Carcinoma / diagnosis*
  • Carcinoma / surgery
  • Chronic Disease
  • Decompression, Surgical
  • Diagnosis, Differential
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Maxillary Sinus Neoplasms / complications
  • Maxillary Sinus Neoplasms / diagnosis*
  • Maxillary Sinus Neoplasms / surgery
  • Optic Nerve / diagnostic imaging*
  • Optic Nerve Diseases / complications*
  • Optic Nerve Diseases / diagnosis
  • Optic Nerve Diseases / surgery
  • Sinusitis / diagnosis*
  • Tomography, X-Ray Computed / methods
  • Vision, Low / diagnosis
  • Vision, Low / etiology*
  • Vision, Low / surgery

Supplementary concepts

  • Sinonasal undifferentiated carcinoma