Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties

Magdalena Malachowska-Ugarte; Claudio Sperduto; Yuri V Ermolovich; Alina L Sauchuk; Michal Jurášek; Raisa P Litvinovskaya; Darya Straltsova; Igor Smolich; Vladimir N Zhabinskii; Pavel Drašar; Vadim Demidchik; Vladimir A Khripach

doi:10.1016/j.steroids.2015.07.002

Brassinosteroid-BODIPY conjugates: Design, synthesis, and properties

Steroids. 2015 Oct:102:53-9. doi: 10.1016/j.steroids.2015.07.002. Epub 2015 Jul 22.

Affiliations

¹ Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevich Str., 5/2, 220141 Minsk, Belarus; University of Chemistry and Technology, Technická 5, CZ-166 28 Praha 6, Czech Republic.
² Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevich Str., 5/2, 220141 Minsk, Belarus.
³ University of Chemistry and Technology, Technická 5, CZ-166 28 Praha 6, Czech Republic.
⁴ Department of Plant Cell Biology and Bioengineering, Biological Faculty, Belarusian State University, Minsk, Belarus.
⁵ Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus, Kuprevich Str., 5/2, 220141 Minsk, Belarus. Electronic address: vz@iboch.bas-net.by.

PMID: 26210210
DOI: 10.1016/j.steroids.2015.07.002

Abstract

Three BS-BODIPY (brassinosteroids-4,4-difluoro-4-bora-3a,4a-diaza-s-indacene) conjugates were synthesized and their fluorescent and immunological properties were investigated. Two of the conjugates, having present all the functional groups characteristic of BS, were shown to be potentially useful as biological probes to study involvement of BS into physiological processes in living cells.

Keywords: BODIPY; Brassinosteroids; Castasterone; Conjugates; Epibrassinolide; Epicastasterone.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Boron Compounds / chemistry*
Brassinosteroids / chemistry*

Substances

4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
Boron Compounds
Brassinosteroids