Assessment of dietary nitrate intake by a self-administered questionnaire and by overnight urinary measurement

Int J Epidemiol. 1989 Dec;18(4):852-7. doi: 10.1093/ije/18.4.852.

Abstract

The relationship between dietary intake and urinary excretion of nitrate was investigated among 35 male and 24 female graduate students in Boston. The dietary assessment method consisted of a self-administered semi-quantitative food frequency questionnaire currently used for large-scale epidemiological studies. Calculated mean daily nitrate intake was 1.83 mmol for men and 2.96 mmol for women; broccoli and green leafy vegetables accounted for 60% of the total. Urinary measurements involved two overnight specimens with a mean collection time of approximately 13 hours. The ratio of intra-to-inter individual variance in urinary nitrate excretion (lambda) was 1.87. The simple correlation coefficient between intake and excretion of nitrate was found to be 0.20; after correction for the within-person variation by using lambda, the correlation coefficient was 0.28. Adjustment for gender, age and Quetelet's index in multiple regression analyses resulted in a partial correlation coefficient between nitrate intake and excretion of 0.37 (p = 0.005). Correction for within-person variation in urinary excretion increased this partial correlation coefficient between intake and excretion to 0.59 (95% CI = 0.03 to 0.87). These data suggest that a self-administered questionnaire may provide useful information on usual nitrate intake, and indicate the need to pursue this possibility further.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Activity Cycles*
  • Adult
  • Analysis of Variance
  • Circadian Rhythm*
  • Female
  • Food*
  • Humans
  • Male
  • Nitrates / administration & dosage
  • Nitrates / urine*
  • Random Allocation
  • Self Disclosure*
  • Surveys and Questionnaires

Substances

  • Nitrates