Prosthetic joint infections in the elderly

Infection. 2015 Dec;43(6):629-37. doi: 10.1007/s15010-015-0806-6. Epub 2015 Jun 22.

Abstract

Introduction: Recent age-projection showed that the number of elderly is expected to rise significantly over the next decades worldwide. Accordingly, the prevalence of chronic and degenerative diseases will increase, among them osteoarthritis, resulting in more and older patients undergoing total joint arthroplasty and thereby also being at risk for associated complications. Among those, prosthetic joint infections are feared as threatening complication with a mortality approaching 8 % and causing long-term antibiotic therapy, immobilization and often account for operative revision.

Materials and methods: This review summarizes epidemiological, microbiological, and therapeutic aspects of prosthetic joint infection in the elderly population.

Conclusion: Considering the increase in the number of PJIs in the forthcoming years in most countries, a common action to reduce the associated morbidity and mortality is strongly encouraged in Europe.

Keywords: Elderly; Management; Prosthetic joint infection; Risk factors; Therapy.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Europe / epidemiology
  • Humans
  • Incidence
  • Osteoarthritis / epidemiology*
  • Osteoarthritis / microbiology
  • Osteoarthritis / therapy
  • Prosthesis-Related Infections / epidemiology*
  • Prosthesis-Related Infections / microbiology
  • Prosthesis-Related Infections / therapy
  • Survival Analysis

Substances

  • Anti-Bacterial Agents