Overexpression of the Arabidopsis thaliana signalling peptide TAXIMIN1 affects lateral organ development

J Exp Bot. 2015 Aug;66(17):5337-49. doi: 10.1093/jxb/erv291. Epub 2015 Jun 12.

Abstract

Lateral organ boundary formation is highly regulated by transcription factors and hormones such as auxins and brassinosteroids. However, in contrast to many other developmental processes in plants, no role for signalling peptides in the regulation of this process has been reported yet. The first characterization of the secreted cysteine-rich TAXIMIN (TAX) signalling peptides in Arabidopsis is presented here. TAX1 overexpression resulted in minor alterations in the primary shoot and root metabolome, abnormal fruit morphology, and fusion of the base of cauline leaves to stems forming a decurrent leaf attachment. The phenotypes at the paraclade junction match TAX1 promoter activity in this region and are similar to loss of LATERAL ORGAN FUSION (LOF) transcription factor function. Nevertheless, TAX1 expression was unchanged in lof1lof2 paraclade junctions and, conversely, LOF gene expression was unchanged in TAX1 overexpressing plants, suggesting TAX1 may act independently. This study identifies TAX1 as the first plant signalling peptide influencing lateral organ separation and implicates the existence of a peptide signal cascade regulating this process in Arabidopsis.

Keywords: Boundary genes; cysteine-rich peptide; fruit development; lateral organ fusion; paraclade junction..

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Arabidopsis / genetics*
  • Arabidopsis / growth & development*
  • Arabidopsis / metabolism
  • Arabidopsis Proteins / chemistry
  • Arabidopsis Proteins / genetics*
  • Arabidopsis Proteins / metabolism
  • Gene Expression Regulation, Plant*
  • Intracellular Signaling Peptides and Proteins / chemistry
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Intracellular Signaling Peptides and Proteins / metabolism
  • Meristem / genetics
  • Meristem / growth & development
  • Meristem / metabolism
  • Peptides / chemistry
  • Peptides / genetics
  • Peptides / metabolism
  • Plant Leaves / genetics
  • Plant Leaves / growth & development
  • Plant Leaves / metabolism
  • Plant Stems / genetics
  • Plant Stems / growth & development
  • Plant Stems / metabolism
  • Protein Sorting Signals
  • Sequence Alignment

Substances

  • Arabidopsis Proteins
  • Intracellular Signaling Peptides and Proteins
  • Peptides
  • Protein Sorting Signals
  • TAX1 protein, Arabidopsis