PET/CT in primary mediastinal large B-cell lymphoma responding to rituximab-CHOP: An analysis of 106 patients regarding prognostic significance and implications for subsequent radiotherapy

T P Vassilakopoulos; G A Pangalis; S Chatziioannou; S Papageorgiou; M K Angelopoulou; Z Galani; G Kourti; V Prassopoulos; T Leonidopoulou; E Terpos; M N Dimopoulou; S Sachanas; C Kalpadakis; P Konstantinidou; D Boutsis; E Stefanoudaki; L Kyriazopoulou; M P Siakantaris; M-C Kyrtsonis; E Variami; I Kotsianidis; A Symeonidis; E Michali; E Katodritou; G Kokkini; C Tsatalas; H Papadaki; M-A Dimopoulos; V Sotiropoulos; V Pappa; T Karmiris; J Meletis; J Apostolidis; I Datseris; P Panayiotidis; K Konstantopoulos; P Roussou; P Rondogianni

doi:10.1038/leu.2015.120

PET/CT in primary mediastinal large B-cell lymphoma responding to rituximab-CHOP: An analysis of 106 patients regarding prognostic significance and implications for subsequent radiotherapy

Leukemia. 2016 Jan;30(1):238-42. doi: 10.1038/leu.2015.120. Epub 2015 May 14.

Authors

T P Vassilakopoulos¹, G A Pangalis², S Chatziioannou³, S Papageorgiou⁴, M K Angelopoulou¹, Z Galani⁵, G Kourti⁶, V Prassopoulos⁷, T Leonidopoulou⁸, E Terpos⁹, M N Dimopoulou¹, S Sachanas², C Kalpadakis¹⁰, P Konstantinidou¹¹, D Boutsis¹², E Stefanoudaki¹³, L Kyriazopoulou¹⁴, M P Siakantaris¹⁵, M-C Kyrtsonis¹⁶, E Variami¹⁵, I Kotsianidis¹⁷, A Symeonidis¹⁸, E Michali¹⁹, E Katodritou¹¹, G Kokkini⁸, C Tsatalas¹⁷, H Papadaki¹⁰, M-A Dimopoulos⁹, V Sotiropoulos²⁰, V Pappa⁴, T Karmiris⁶, J Meletis¹, J Apostolidis⁶, I Datseris²¹, P Panayiotidis¹⁶, K Konstantopoulos¹, P Roussou⁵, P Rondogianni²¹

Affiliations

¹ Department of Haematology, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
² Department of Haematology, Athens Medical Center, Psychikon Branch, Athens, Greece.
³ Department of Nuclear Medicine, National and Kapodistrian University of Athens, Sotiria Hospital, Athens, Greece.
⁴ Second Propedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Attikon Hospital, Athens, Greece.
⁵ Third Department of Internal Medicine, National and Kapodistrian University of Athens, Sotiria Hospital, Athens, Greece.
⁶ Department of Haematology and Lymphoma, Evangelismos General Hospital, Athens, Greece.
⁷ Department of Nuclear Medicine, HYGEIA Hospital, Athens, Greece.
⁸ Department of Haematology, Sismanoglion General Hospital, Athens, Greece.
⁹ Department of Therapeutics, National and Kapodistrian University of Athens, Alexandra Hospital, Athens, Greece.
¹⁰ Department of Haematology, University of Crete, Iraklion, Greece.
¹¹ Department of Haematology, Theagenion Anticancer General Hospital, Thessaloniki, Greece.
¹² Department of Haematology, Athens Navy Hospital, Athens, Greece.
¹³ Department of Haematology, Amalia Fleming Hospital, Athens, Greece.
¹⁴ Department of Haematology, University of Ioannina, Ioannina, Greece.
¹⁵ First Department of Internal Medicine, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
¹⁶ First Propedeutic Department of Internal Medicine, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
¹⁷ Department of Haematology, Democritus University of Thrace, Alexandroupolis, Greece.
¹⁸ Hematology Division, Department of Internal Medicine, University of Patras, Patras, Greece.
¹⁹ Department of Clinical Haematology, "G.Gennimatas" Athens General Hospital, Athens, Greece.
²⁰ Department of Nuclear Medicine and PET/CT, Athens Medical Center, Athens, Greece.
²¹ Department of Nuclear Medicine and PET/CT, Evangelismos General Hospital, Athens, Greece.

PMID: 25971363
DOI: 10.1038/leu.2015.120

No abstract available

Publication types

Letter

MeSH terms

Adolescent
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / administration & dosage
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Cyclophosphamide / administration & dosage
Doxorubicin / administration & dosage
Female
Humans
Lymphoma, Large B-Cell, Diffuse / diagnostic imaging*
Lymphoma, Large B-Cell, Diffuse / drug therapy
Lymphoma, Large B-Cell, Diffuse / mortality
Male
Mediastinal Neoplasms / diagnostic imaging*
Mediastinal Neoplasms / drug therapy
Mediastinal Neoplasms / mortality
Middle Aged
Positron-Emission Tomography
Prednisone / administration & dosage
Prognosis
Rituximab / administration & dosage
Tomography, X-Ray Computed
Vincristine / administration & dosage

Substances

Rituximab
Vincristine
Doxorubicin
Cyclophosphamide
Prednisone

Supplementary concepts

CHOP protocol