Prevalence, knowledge, and treatment of transient ischemic attacks in China

Yilong Wang; Xingquan Zhao; Yong Jiang; Hao Li; Limin Wang; S Claiborne Johnston; Liping Liu; Ka Sing Lawrence Wong; Chunxue Wang; Yuesong Pan; Jing Jing; Jie Xu; Xia Meng; Mei Zhang; Yichong Li; Yong Zhou; Wenhua Zhao; Yongjun Wang

doi:10.1212/WNL.0000000000001665

Prevalence, knowledge, and treatment of transient ischemic attacks in China

Neurology. 2015 Jun 9;84(23):2354-61. doi: 10.1212/WNL.0000000000001665. Epub 2015 May 8.

Authors

Yilong Wang¹, Xingquan Zhao², Yong Jiang², Hao Li², Limin Wang², S Claiborne Johnston², Liping Liu², Ka Sing Lawrence Wong², Chunxue Wang², Yuesong Pan², Jing Jing², Jie Xu², Xia Meng², Mei Zhang², Yichong Li², Yong Zhou², Wenhua Zhao², Yongjun Wang¹

Affiliations

¹ From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China. yongjunwang1962@gmail.com yilong528@gmail.com.
² From the Department of Neurology (Yilong Wang, X.Z., Y.J., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing Tiantan Hospital, Capital Medical University, Beijing; China National Clinical Research Center for Neurological Diseases (Yilong Wang, X.Z., H.L., L.L., C.W., Y.P., J.J., J.X., X.M., Y.Z., Yongjun Wang), Beijing; National Center for Chronic and Non-communicable Disease Control and Prevention (Y.J., L.W., M.Z., Y.L.), Chinese Center for Disease Control and Prevention (W.Z.), Beijing, China; Departments of Neurology and Epidemiology (S.C.J.), University of California, San Francisco; and Division of Neurology (K.S.L.W.), Department of Medicine and Therapeutics, the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China.

Abstract

Objectives: To investigate the prevalence, knowledge, and treatment of TIA in a Chinese adult population.

Methods: We conducted a complex, multistage, probability sampling-designed, cross-sectional, nationwide survey of 98,658 Chinese adults in 2010. Possible TIA cases were first identified by symptoms recall or self-reported history of TIA through face-to-face interviews, and the final diagnosis was then made by expert neurologists through phone interviews or record review.

Results: The age-standardized prevalence of TIA was 2.27%. Clinically, only 16.0% of the participants were diagnosed before the study. The prevalence of TIA was higher in women and in patients who were older, had less education, were current smokers, lived in rural or undeveloped areas, and had a history of stroke, hypertension, myocardial infarction, dyslipidemia, or diabetes. Based on the survey responses, approximately 3.08% of Chinese adults had knowledge of TIA. Among patients with TIA, only 5.02% received treatment and 4.07% received guideline-recommended therapy.

Conclusions: TIA is prevalent and an estimated 23.9 million people in China may have experienced a TIA. Public knowledge on TIA is very limited. TIA appears to be largely undiagnosed and untreated in China. There is an urgent need to develop strategies to improve the identification and appropriate management of TIA.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
China / epidemiology
Cross-Sectional Studies
Female
Health Knowledge, Attitudes, Practice*
Humans
Ischemic Attack, Transient / epidemiology*
Ischemic Attack, Transient / therapy
Male
Middle Aged
Prevalence
Young Adult