Multidrug-resistant Salmonella enterica serotype Typhi, Gulf of Guinea Region, Africa

Emerg Infect Dis. 2015 Apr;21(4):655-9. doi: 10.3201/eid2104.141355.

Abstract

We identified 3 lineages among multidrug-resistant (MDR) Salmonella enterica serotype Typhi isolates in the Gulf of Guinea region in Africa during the 2000s. However, the MDR H58 haplotype, which predominates in southern Asia and Kenya, was not identified. MDR quinolone-susceptible isolates contained a 190-kb incHI1 pST2 plasmid or a 50-kb incN pST3 plasmid.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Drug Resistance, Multiple, Bacterial*
  • Genetic Variation
  • Geography
  • Guinea / epidemiology
  • Haplotypes
  • Humans
  • Microbial Sensitivity Tests
  • Polymorphism, Single Nucleotide
  • Salmonella typhi / drug effects*
  • Salmonella typhi / genetics
  • Typhoid Fever / epidemiology*
  • Typhoid Fever / microbiology*

Substances

  • Anti-Bacterial Agents