EpiToolKit--a web-based workbench for vaccine design

Benjamin Schubert; Hans-Philipp Brachvogel; Christopher Jürges; Oliver Kohlbacher

doi:10.1093/bioinformatics/btv116

EpiToolKit--a web-based workbench for vaccine design

Bioinformatics. 2015 Jul 1;31(13):2211-3. doi: 10.1093/bioinformatics/btv116. Epub 2015 Feb 20.

Authors

Benjamin Schubert¹, Hans-Philipp Brachvogel², Christopher Jürges², Oliver Kohlbacher³

Affiliations

¹ Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany.
² Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany.
³ Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany Center for Bioinformatics, University of Tübingen, 72076 Tübingen, Germany, Applied Bioinformatics, Department of Computer Science, 72076 Tübingen, Germany, Quantitative Biology Center, 72076 Tübingen, Germany and Faculty of Medicine, University of Tübingen, 72076 Tübingen, Germany.

Abstract

EpiToolKit is a virtual workbench for immunological questions with a focus on vaccine design. It offers an array of immunoinformatics tools covering MHC genotyping, epitope and neo-epitope prediction, epitope selection for vaccine design, and epitope assembly. In its recently re-implemented version 2.0, EpiToolKit provides a range of new functionality and for the first time allows combining tools into complex workflows. For inexperienced users it offers simplified interfaces to guide the users through the analysis of complex immunological data sets.

Availability and implementation: http://www.epitoolkit.de

Contact: schubert@informatik.uni-tuebingen.de

Supplementary information: Supplementary data are available at Bioinformatics online.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Computational Biology / methods*
Epitopes / chemistry*
Humans
Internet*
Major Histocompatibility Complex / genetics
Major Histocompatibility Complex / immunology*
Proteins / immunology*
Software*
Vaccines / chemistry
Vaccines / immunology*

Substances

Epitopes
Proteins
Vaccines