Isolation and characterization of two mitoviruses and a putative alphapartitivirus from Fusarium spp

Virus Genes. 2015 Jun;50(3):466-73. doi: 10.1007/s11262-015-1182-0. Epub 2015 Feb 17.

Abstract

The filamentous fungus Fusarium spp. includes several important plant pathogens. We attempted to reveal presence of double-stranded (ds) RNAs in the genus. Thirty-seven Fusarium spp. at the MAFF collection were analyzed. In the strains of Fusarium coeruleum, Fusarium globosum and Fusarium solani f. sp. pisi, single dsRNA bands were detected. The strains of F. coeruleum and F. solani f. sp. pisi cause potato dry rot and mulberry twig blight, respectively. Sequence analyses revealed that dsRNAs in F. coeruleum and F. globosum consisted of 2423 and 2414 bp, respectively. Using the fungal mitochondrial translation table, the positive strands of these cDNAs were found to contain single open reading frames with the potential to encode a protein of putative 757 and 717 amino acids (molecular mass 88.5 and 84.0 kDa, respectively), similar to RNA-dependent RNA polymerases of members of the genus Mitovirus. These dsRNAs in F. coeruleum and F. globosum were assigned to the genus Mitovirus (family Narnaviridae), and these two mitoviruses were designated as Fusarium coeruleum mitovirus 1 and Fusarium globosum mitovirus 1. On the other hand, a positive strand of cDNA (1950 bp) from dsRNA in F. solani f. sp. pisi contained an ORF potentially encoding a putative RdRp of 608 amino acids (72.0 kDa). The putative RdRp was shown to be related to those of members of the genus of Alphapartitivirus (family Partitiviridae). We coined the name Fusarium solani partitivirus 2 for dsRNA in F. solani f. sp. pisi.

MeSH terms

  • Cluster Analysis
  • Fusarium / isolation & purification
  • Fusarium / virology*
  • Models, Molecular
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • Open Reading Frames
  • Plant Diseases / microbiology
  • RNA Viruses / genetics*
  • RNA Viruses / isolation & purification*
  • RNA, Double-Stranded / genetics*
  • RNA, Viral / genetics*
  • Sequence Analysis, DNA
  • Sequence Homology

Substances

  • RNA, Double-Stranded
  • RNA, Viral

Associated data

  • GENBANK/LC006128
  • GENBANK/LC006129
  • GENBANK/LC006130