[Whole brain radiation therapy for brain metastases: Advantages and controversies]

Cancer Radiother. 2015 Feb;19(1):30-5. doi: 10.1016/j.canrad.2014.12.004. Epub 2015 Feb 7.
[Article in French]

Abstract

Whole brain radiation therapy is the angular stone of the brain metastasis radiation therapy. This treatment allows reaching two goals, potentially curative for in place metastasis and prophylactic in the rest of brain tissue. However, these two advantages can be disputed and in light of the same data opposite conclusions could be drawn.

Keywords: Brain metastases; Curative treatment; Guidelines; Irradiation encéphalique en totalité; Métastases cérébrales; Prophylactic treatment; Référentiel; Traitement curatif; Traitement prophylactique; Whole brain radiation therapy.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Alopecia / etiology
  • Brain / pathology
  • Brain / radiation effects
  • Brain Neoplasms / drug therapy
  • Brain Neoplasms / prevention & control
  • Brain Neoplasms / radiotherapy
  • Brain Neoplasms / secondary*
  • Combined Modality Therapy
  • Cranial Irradiation* / adverse effects
  • Cranial Irradiation* / methods
  • Humans
  • Memory Disorders / etiology
  • Multicenter Studies as Topic
  • Necrosis
  • Neoplasm Recurrence, Local / radiotherapy
  • Prospective Studies
  • Radiation Injuries / etiology
  • Radiation-Sensitizing Agents / therapeutic use
  • Survival Analysis
  • Treatment Outcome

Substances

  • Adrenal Cortex Hormones
  • Radiation-Sensitizing Agents