Simplified Selvester Score: a practical electrocardiographic instrument to predict response to CRT

J Electrocardiol. 2015 Jan-Feb;48(1):62-8. doi: 10.1016/j.jelectrocard.2014.10.014. Epub 2014 Nov 4.

Abstract

Aims: To investigate the LBBB Selvester Scoring System (LBBB-SSc) and the Simplified-SSc prognostic impact in predicting response to CRT, all cause and cardiac mortality, heart failure (HF) hospitalizations and onset of arrhythmias in HF patients undergoing CRT.

Methods: We retrospectively evaluated LBBB-SSc and Simplified-SSc of 172 consecutive HF patients with true-LBBB who underwent CRT. Response to CRT was defined as the improvement of LVEF of at least 10% or as the reduction of LVESV of at least 15% at 6-month follow-up. Logistic regression analysis and Cox proportional hazard analysis were performed to evaluate each endpoint related risk according to LBBB-SSc and Simplified-SSc.

Results: The LBBB-SSc and the Simplified-SSc were inversely correlated with response to CRT. Myocardial scar at both scores was independently associated to non-response to CRT. No correlation was observed between LBBB-SSc or Simplified-SSc and other endpoints.

Conclusions: In HF patients with true-LBBB, Simplified-SSc is able to predict response to CRT.

Keywords: Cardiac Resynchronization Therapy; Heart failure; Myocardial fibrosis; Reverse remodeling; Selvester QRS Score.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Bundle-Branch Block / diagnosis*
  • Bundle-Branch Block / mortality*
  • Bundle-Branch Block / therapy*
  • Cardiac Resynchronization Therapy / mortality*
  • Electrocardiography / methods*
  • Electrocardiography / statistics & numerical data
  • Female
  • Humans
  • Italy / epidemiology
  • Male
  • Prevalence
  • Prognosis
  • Reproducibility of Results
  • Retrospective Studies
  • Risk Factors
  • Sensitivity and Specificity
  • Severity of Illness Index*
  • Survival Rate
  • Treatment Outcome