What is new in systemic lupus erythematosus

Reumatol Clin. 2015 Jan-Feb;11(1):27-32. doi: 10.1016/j.reuma.2014.09.004. Epub 2014 Nov 11.
[Article in English, Spanish]

Abstract

Systemic lupus erythematosus is a heterogeneous rheumatic systemic disease with extremely varied clinical manifestations and a diverse pathogenesis, as illustrated in this review on the most relevant new knowledge related to the disease. Topics such as anemia, pathogenesis, cardiovascular risk assessment, antiphospholipid syndrome, prediction of damage and recent advances in treatment, including tolerogenic and biological agents, are discussed. Relevant contributions regarding classical therapies such as corticosteroid and antimalarials and their optimal use, as well as the roll of vitamin D, are also referred.

Keywords: Lupus eritematoso sistémico; Systemic lupus erythematosus.

Publication types

  • Review

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Antiphospholipid Syndrome / etiology
  • Biological Factors / therapeutic use
  • Cardiovascular Diseases / etiology
  • Disease Progression
  • Humans
  • Lupus Erythematosus, Systemic* / drug therapy
  • Lupus Erythematosus, Systemic* / etiology
  • Lupus Erythematosus, Systemic* / immunology
  • Lupus Erythematosus, Systemic* / physiopathology
  • Risk Factors
  • Vitamin D / therapeutic use
  • Vitamins / therapeutic use

Substances

  • Anti-Inflammatory Agents
  • Biological Factors
  • Vitamins
  • Vitamin D