Psychosocial factors and adherence to drug treatment in patients on chronic haemodialysis

Nefrologia. 2014 Nov 17;34(6):737-42. doi: 10.3265/Nefrologia.pre2014.Jul.12477.
[Article in English, Spanish]

Abstract

Background: The daily pill burden in hemodialysis patients is one of the highest reported to date in any chronic disease. The adherence to prescribed treatment has implications on the quality of life, the survival of patients, and the economic cost of their treatment, this being a priority public health issue.

Objective: To evaluate the adherence to pharmacological treatment examining, among the possible causes of non-adherence, psychosocial factors such as depression, anxiety, cognitive impairment and social support.

Method: Transversal-observational study of thirty five patients that suffer from chronic renal disease and who are on manteinance hemodialysis, evaluated by self-reported measures.

Results: Non-adherent patients have significant higher depression index than adherent patients. Anxiety, cognitive impairment and social support do not show a significant relation with the degree of adherence or compliance with farmacological treatment.

Conclusions: These results suggest that psychological intervention in chronic haemodialysis patients with a severe depression index could increase the degree of fulfillment and general well-being of renal patients.

Publication types

  • Observational Study

MeSH terms

  • Anxiety / etiology
  • Cognition Disorders / etiology
  • Comorbidity
  • Cross-Sectional Studies
  • Depression / etiology
  • Diabetic Nephropathies / drug therapy
  • Diabetic Nephropathies / psychology
  • Diabetic Nephropathies / therapy
  • Humans
  • Kidney Failure, Chronic / drug therapy
  • Kidney Failure, Chronic / psychology*
  • Kidney Failure, Chronic / therapy
  • Medication Adherence*
  • Polypharmacy
  • Psychology
  • Quality of Life
  • Renal Dialysis / psychology*
  • Self Report
  • Severity of Illness Index
  • Social Support
  • Spain