Impact of a palliative care program on end-of-life care in a neonatal intensive care unit

J Perinatol. 2015 Mar;35(3):218-22. doi: 10.1038/jp.2014.193. Epub 2014 Oct 23.

Abstract

Objective: Evaluate changes in end-of-life care following initiation of a palliative care program in a neonatal intensive care unit.

Study design: Retrospective study comparing infant deaths before and after implementation of a Palliative Care Program comprised of medication guidelines, an individualized order set, a nursing care plan and staff education.

Result: Eighty-two infants died before (Era 1) and 68 infants died after implementation of the program (Era 2). Morphine use was similar (88% vs 81%; P =0.17), whereas benzodiazepines use increased in Era 2 (26% vs 43%; P=0.03). Withdrawal of life support (73% vs 63%; P=0.17) and do-not-resuscitate orders (46% vs 53%; P=0.42) were similar. Do-not-resuscitate orders and family meetings were more frequent among Era 2 infants with activated palliative care orders (n=21) compared with infants without activated orders (n=47).

Conclusion: End-of-life family meetings and benzodiazepine use increased following implementation of our program, likely reflecting adherence to guidelines and improved communication.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Benzodiazepines / therapeutic use*
  • Cause of Death
  • Female
  • Humans
  • Infant
  • Infant Death
  • Infant, Newborn
  • Intensive Care Units, Neonatal / organization & administration*
  • Male
  • Morphine / therapeutic use*
  • Palliative Care*
  • Resuscitation Orders
  • Retrospective Studies
  • Terminal Care*
  • Withholding Treatment

Substances

  • Benzodiazepines
  • Morphine