Current status of kidney transplantation in HIV-infected patients

Curr Opin Nephrol Hypertens. 2014 Nov;23(6):619-24. doi: 10.1097/MNH.0000000000000071.

Abstract

Purpose of review: To summarize the most current literature on transplant outcomes in HIV-infected kidney recipients.

Recent findings: HIV-infected recipients overall have excellent patient and allograft outcomes. Acute rejection, delayed graft function, drug-drug interactions and limited access to organs have emerged as important issues for HIV-infected kidney transplant patients. The subset of patients who are coinfected with hepatitis C virus do not fare as well and improving their outcomes should be a focus of future research in the field.

Summary: Renal transplantation remains the optimal treatment for end stage renal disease in the HIV-infected patient.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • AIDS-Associated Nephropathy / diagnosis
  • AIDS-Associated Nephropathy / surgery*
  • AIDS-Associated Nephropathy / virology
  • Antiretroviral Therapy, Highly Active
  • Donor Selection
  • Health Services Accessibility
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Kidney Failure, Chronic / diagnosis
  • Kidney Failure, Chronic / surgery*
  • Kidney Failure, Chronic / virology
  • Kidney Transplantation* / adverse effects
  • Patient Selection
  • Risk Assessment
  • Risk Factors
  • Tissue Donors / supply & distribution
  • Treatment Outcome

Substances

  • Immunosuppressive Agents