First report of human Trypanosoma cruzi infection attributed to TcBat genotype

Zoonoses Public Health. 2014 Nov;61(7):477-9. doi: 10.1111/zph.12094. Epub 2013 Dec 19.

Abstract

Chagas disease is an endemic disease of the American continent caused by Trypanosoma cruzi and divided into six discrete typing units (TcI - TcVI). Nearly 10 million people harbour the infection representing a serious issue in public health. Epidemiological surveillance allowed us to detect a bat-related T. cruzi genotype (henceforth named TcBat) in a 5-year-old female living in a forest area in northwestern Colombia. Molecular tools determined a mixed infection of T. cruzi I and TcBat genotypes. This represents the first report of TcBat infection in humans; the epidemiological consequences of this finding are discussed herein.

Keywords: Chagas disease; bats; discrete typing units; genotypes; human infection.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chagas Disease / blood
  • Chagas Disease / epidemiology
  • Chagas Disease / transmission*
  • Child, Preschool
  • Chiroptera / parasitology
  • Colombia / epidemiology
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Genotype
  • Humans
  • Population Surveillance
  • Trypanosoma cruzi* / genetics
  • Zoonoses / parasitology*
  • Zoonoses / transmission