An eye-tracking investigation of intentional motion perception in patients with schizophrenia

J Psychiatry Neurosci. 2015 Mar;40(2):118-25. doi: 10.1503/jpn.140065.

Abstract

Background: Schizophrenia has been characterized by an impaired attribution of intentions in social interactions. However, it remains unclear to what extent poor performance may be due to low-level processes or to later, higher-level stages or to what extent the deficit reflects an over- (hypermentalization) or underattribution of intentions (hypomentalization).

Methods: We evaluated intentional motion perception using a chasing detection paradigm in individuals with schizophrenia or schizoaffective disorder and in healthy controls while eye movements were recorded. Smooth pursuit was measured as a control task. Eye-tracking was used to dissociate ocular from cognitive stages of processing.

Results: We included 27 patients with schizophrenia, 2 with schizoaffective disorder and 29 controls in our analysis. As a group, patients had lower sensitivity to the detection of chasing than controls, but showed no bias toward the chasing present response. Patients showed a slightly different visual exploration strategy, which affected their ocular sensitivity to chasing. They also showed a decreased cognitive sensitivity to chasing that was not explained by differences in smooth pursuit ability, in visual exploration strategy or in general cognitive abilities.

Limitations: It is not clear whether the deficit in intentional motion detection demonstrated in this study might be explained by a general deficit in motion perception in individuals with schizophrenia or whether it is specific to the social domain.

Conclusion: Participants with schizophrenia showed a hypomentalization deficit: they adopted suboptimal visual exploration strategies and had difficulties deciding whether a chase was present or not, even when their eye movement revealed that chasing information had been seen correctly.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cognition
  • Eye Movement Measurements
  • Eye Movements*
  • Female
  • Humans
  • Male
  • Models, Psychological
  • Motion Perception*
  • Neuropsychological Tests
  • Photic Stimulation
  • Psychotic Disorders / physiopathology
  • Psychotic Disorders / psychology*
  • Schizophrenia / physiopathology
  • Schizophrenic Psychology*