[Clinical characteristics of 104 patients with primary gastrointestinal non-Hodgkin lymphoma]

Zhonghua Xue Ye Xue Za Zhi. 2014 Sep;35(9):791-5. doi: 10.3760/cma.j.issn.0253-2727.2014.09.002.
[Article in Chinese]

Abstract

Objective: To analyze the clinical characteristics and prognostic factors in patients with primary gastrointestinal non-Hodgkin lymphoma (PGI-NHL).

Methods: The pathological data of 104 PGI-NHL patients diagnosed in our hospital between 2003 and 2013 were analyzed retrospectively.

Results: 104 patients with PGI-NHL were enrolled, including 58 males and 46 females with a median age of 53 (range:15 to 83) years. 51(49%) cases derived from stomach and the other 53 (51%) patients originated in intestine. The median survival was 35 (range:1 to 30) months. The 1- year, 3- year, and 5-year overall survival (OS) were 88.4%, 80.7% and 78.8%, respectively. Both progress free survival and OS were significantly higher in B-cell GPI-NHL than T- cell GPI-NHL (P=0.000).

Conclusion: The survival of gastric NHL is superior to intestinal NHL. The sites of origin and pathological type are prognostic factors for survival in PGI-NHL patients.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Disease-Free Survival
  • Female
  • Gastrointestinal Neoplasms / diagnosis*
  • Humans
  • Lymphoma, Non-Hodgkin / diagnosis*
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Young Adult