Treatment of vitamin K-dependent coagulation factor deficiency and subarachnoid hemorrhage

World J Emerg Med. 2011;2(1):73-6. doi: 10.5847/wjem.j.1920-8642.2011.01.014.

Abstract

Background: In adults, vitamin K-dependent coagulation factor deficiency (VKCFD) increases in the recent years. We treated a VKCFD patient with subarachnoid hemorrhage, with favorable outcomes.

Methods: A 19-year-old male student with VKCFD was treated at our hospital. The initial treatment was injection of a large dose of vitamin K and fresh plasma, and then with oral high dose of vitamin K4.

Results: At 4 weeks after admission, the focus of hemorrhage subsided, neurological examination was normal, and the patient was discharged.

Conclusions: VKCFD is rare and its diagnosis should be based on the history of the patient and the results of laboratory examinations. A large dose of vitamin K is the first choice of treatment.

Keywords: Diagnosis; Subarachnoid hemorrhage; Vitamin K-dependent coagulation factor deficiency.

Publication types

  • Case Reports