Basophils increase in Crohn disease and ulcerative colitis and favor mesenteric lymph node memory TH17/TH1 response

J Allergy Clin Immunol. 2014 Oct;134(4):978-81.e1. doi: 10.1016/j.jaci.2014.05.025. Epub 2014 Jul 2.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Basophils / immunology*
  • Cell Movement
  • Cell Proliferation
  • Cell Survival
  • Cells, Cultured
  • Colitis, Ulcerative / drug therapy
  • Colitis, Ulcerative / immunology*
  • Crohn Disease / drug therapy
  • Crohn Disease / immunology*
  • Cytokines / immunology*
  • Disease Progression
  • Humans
  • Immunologic Memory
  • Immunosuppressive Agents / therapeutic use
  • Intestinal Mucosa / immunology*
  • Lymph Nodes / immunology*
  • Lymphocyte Activation
  • Mesalamine / therapeutic use
  • Receptors, CCR7 / metabolism
  • Th1 Cells / immunology*
  • Th17 Cells / immunology*
  • Thymic Stromal Lymphopoietin

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • CCR7 protein, human
  • Cytokines
  • Immunosuppressive Agents
  • Receptors, CCR7
  • Mesalamine
  • Thymic Stromal Lymphopoietin