Protein intake and neurodevelopmental outcomes

Bonnie E Stephens; Betty R Vohr

doi:10.1016/j.clp.2014.02.005

Protein intake and neurodevelopmental outcomes

Clin Perinatol. 2014 Jun;41(2):323-9. doi: 10.1016/j.clp.2014.02.005. Epub 2014 Apr 13.

Authors

Bonnie E Stephens¹, Betty R Vohr²

Affiliations

¹ Department of Pediatrics, Warren Alpert Medical School, Brown University, 222 Richmond Street, Providence, RI, USA; NICU, Community Medical Center, 2827 Fort Missoula Road, Missoula, MT 59804, USA. Electronic address: bstephens@communitymed.org.
² Neonatal Follow-up Program, Women and Infants Hospital, Department of Pediatrics, Warren Alpert Medical School, Brown University, 222 Richmond Street, Providence, RI, USA.

PMID: 24873835
DOI: 10.1016/j.clp.2014.02.005

Abstract

There is a compelling body of literature that suggests that the provision of an inadequate amount of protein to preterm infants in the neonatal period has detrimental effects on the developing brain with the potential to result in long-term, neurodevelopmental sequelae. Although a great deal of indirect evidence implies that the provision of adequate amounts of protein may be associated with better neurodevelopmental outcomes, there remains a paucity of direct evidence that would allow us to draw any final conclusions.

Keywords: Neonatal; Neurodevelopment; Outcomes; Prematurity; Protein.

Publication types

Review

MeSH terms

Developmental Disabilities / prevention & control*
Dietary Proteins / administration & dosage*
Humans
Infant Nutritional Physiological Phenomena / physiology*
Infant, Newborn
Infant, Premature / growth & development*
Nutritional Support / methods*

Substances

Dietary Proteins