Predictors for identification of stigmata of recent hemorrhage on colonic diverticula in lower gastrointestinal bleeding

J Clin Gastroenterol. 2015 Mar;49(3):e24-30. doi: 10.1097/MCG.0000000000000140.

Abstract

Goals: The aim of this study was to identify predictors for the identification of stigmata of recent hemorrhage (SRH) on colonic diverticula.

Background: Several factors influence the identification of SRH in the diagnosis of colonic diverticular bleeding.

Study: A total of 396 patients hospitalized for lower gastrointestinal bleeding were analyzed. Comorbidities, medications, timing of colonoscopy [<24 h (h); urgent, 24 to 48 h, >48 h], preparation, expert colonoscopist, use of a cap, use of a water-jet scope, total colonoscopy, and procedure time (over 60 min) were assessed. A multivariable logistic regression model was used to estimate odds ratio (OR) and 95% confidence interval (CI).

Results: Two hundred fifteen patients were diagnosed with colonic diverticular bleeding and 37 (17%) were identified with SRH. Urgent colonoscopy (OR, 8.4; 95% CI, 2.3-30; P<0.01), expert colonoscopist (OR, 3.0; 95% CI, 1.2-7.3; P=0.02), use of a cap (OR, 3.4; 95% CI, 1.4-8.0; P=0.01), and use of water-jet scope (OR, 5.8; 95% CI, 2.3-15; P<0.01) were found to be independent predictive factors for SRH. The accuracy of these factors in combination was 0.90 (95% CI, 0.85-0.96) as measured by area under the receiver operating characteristic curve (ROC-AUC). SRH identification rate was higher in the urgent (22%) than in the 24 to 48 hours (2.9%, P<0.01) and >48 hours groups (1.0%, P<0.01), showing a tendency to decrease with time (P<0.01 for trend).

Conclusions: Factors of urgent colonoscopy, expert colonoscopist, use of a cap, and use of water-jet scope are useful for identifying SRH diverticula.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Ambulatory Care
  • Area Under Curve
  • Blood Transfusion
  • Chi-Square Distribution
  • Clinical Competence
  • Colon / pathology*
  • Colon / surgery
  • Colonoscopy / methods*
  • Diverticulum, Colon / complications*
  • Diverticulum, Colon / pathology*
  • Diverticulum, Colon / therapy
  • Female
  • Gastrointestinal Hemorrhage / etiology*
  • Gastrointestinal Hemorrhage / pathology*
  • Gastrointestinal Hemorrhage / therapy
  • Hemostasis
  • Humans
  • Kaplan-Meier Estimate
  • Length of Stay
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Predictive Value of Tests
  • ROC Curve
  • Recurrence
  • Retrospective Studies
  • Risk Factors
  • Therapeutic Irrigation
  • Time Factors
  • Treatment Outcome