Should clinical studies involving "regenerative injection therapy," strive to incorporate a triad of outcome measures instead of only including clinical outcome measures?

J D Tucker; J J Ericksen; L L Goetz; L W Elmore

doi:10.1016/j.joca.2014.04.005

Should clinical studies involving "regenerative injection therapy," strive to incorporate a triad of outcome measures instead of only including clinical outcome measures?

Osteoarthritis Cartilage. 2014 Jun;22(6):715-7. doi: 10.1016/j.joca.2014.04.005. Epub 2014 Apr 22.

Authors

J D Tucker¹, J J Ericksen², L L Goetz³, L W Elmore⁴

Affiliations

¹ Virginia Commonwealth University, Department of Physical Medicine and Rehabilitation, United States. Electronic address: Jason.Tucker@va.gov.
² The Kaplan Center, McLean, VA, United States.
³ Virginia Commonwealth University and Hunter Holmes McGuire VA Medical Center, Department of Physical Medicine and Rehabilitation, United States.
⁴ Virginia Commonwealth University, Department of Pathology, United States.

PMID: 24769241
DOI: 10.1016/j.joca.2014.04.005

No abstract available

Keywords: Biological mechanism of action; Biomarkers; Growth Factors; Mesenchymal Stem Cells; Platelet rich plasma; Regenerative injection therapy.

Publication types

Editorial

MeSH terms

Biological Products / administration & dosage*
Biological Products / pharmacology
Biomarkers / blood
Cartilage, Articular / drug effects
Cartilage, Articular / physiopathology
Clinical Trials as Topic
Humans
Injections, Intra-Articular
Injections, Subcutaneous
Mesenchymal Stem Cell Transplantation / methods*
Mesenchymal Stem Cells
Osteoarthritis / diagnosis
Osteoarthritis / therapy*
Outcome Assessment, Health Care
Platelet-Rich Plasma
Regenerative Medicine / methods*
Treatment Outcome

Substances

Biological Products
Biomarkers