Effect of false lumen partial thrombosis on repaired acute type A aortic dissection

J Thorac Cardiovasc Surg. 2014 Nov;148(5):2140-2146.e3. doi: 10.1016/j.jtcvs.2014.02.003. Epub 2014 Feb 12.

Abstract

Objective: Studies on the partial thrombosis of a false lumen after repairing a type A acute aortic dissection (TAAAD) have reported conflicting results. We investigated the effects of a partially thrombosed false lumen on the segmental growth rates, distal aortic reoperations, and long-term survival.

Methods: The postoperative computed tomography scans of 67 patients were retrospectively reviewed. A false lumen was independently defined at 3 segments of the descending thoracic aorta (DTA) on the last follow-up computed tomography scan: the proximal segment near the aortic arch, the distal segment near the diaphragm, and the middle segment.

Results: The segmental aortic growth rate of completely thrombosed, completely patent, and partially thrombosed false lumens was -0.10±0.31, 0.09±0.22, and 0.35±0.60 mm/mo at the proximal DTA (P=.001), -0.04±0.18, 0.12±0.19, and 0.28±0.28 mm/mo at the middle DTA (P<.001), and -0.02±0.13, 0.07±0.07, and 0.16±0.14 mm/mo at the distal DTA (P<.001), respectively. The corresponding freedom from reoperation rates for the proximal DTA at 10 years were 100%, 88%, and 62% (P=.013). The overall 10-year survival rate was 89% and was not significantly different among the study groups.

Conclusions: Partial thrombosis at each segment of a residual false lumen after TAAAD repair correlated with a faster regional aortic growth rate and predicted a greater reoperation rate but did not affect long-term overall survival.

MeSH terms

  • Acute Disease
  • Adult
  • Aorta, Thoracic / diagnostic imaging
  • Aorta, Thoracic / surgery*
  • Aortic Aneurysm, Thoracic / diagnostic imaging
  • Aortic Aneurysm, Thoracic / mortality
  • Aortic Aneurysm, Thoracic / surgery*
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / mortality
  • Aortic Dissection / surgery*
  • Aortography / methods
  • Female
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Reoperation
  • Retrospective Studies
  • Risk Factors
  • Thrombosis* / diagnostic imaging
  • Thrombosis* / surgery
  • Time Factors
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Vascular Surgical Procedures* / adverse effects
  • Vascular Surgical Procedures* / mortality