Incidence of hypercoagulable events after image-guided percutaneous cryoablation of renal tumors: a single-center experience

J Vasc Interv Radiol. 2014 May;25(5):776-9. doi: 10.1016/j.jvir.2014.01.027. Epub 2014 Mar 18.

Abstract

Purpose: To identify retrospectively hypercoagulable events that occurred over time in patients who underwent image-guided percutaneous renal cryoablation and compare the incidence with a cohort of patients who underwent surgical partial nephrectomy (PN) during the same time period.

Materials and methods: An electronic medical record database was queried for patients who underwent percutaneous image-guided renal mass cryoablation or PN between September 2006 and June 2012. Records were examined for thrombotic events during the year following the procedure in each group. Incidence rates, Kaplan-Meier estimates, and patient demographic variables were compared using the stratified log-rank test and t test for independent samples.

Results: The study comprised 114 cryoablation cases. The cumulative incidence of thrombotic events after 1 year was 4.39%. The incidence per 100 person-years was 4.84. There were 105 PN cases. The cumulative incidence of thrombotic events after 1 year was 1.0%. The incidence per 100 person-years was 1.14. The person-time incidence rate difference for these two groups did not reach statistical significance (P = .0894).

Conclusions: The incidence of thrombotic events in patients who underwent percutaneous renal cryoablation in this study was not significantly different than a comparable cohort who underwent surgical PN during the same time period.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Causality
  • Comorbidity
  • Cryosurgery / statistics & numerical data*
  • Female
  • Humans
  • Incidence
  • Kidney Neoplasms / diagnostic imaging
  • Kidney Neoplasms / epidemiology
  • Kidney Neoplasms / surgery*
  • Male
  • Middle Aged
  • Nephrectomy / statistics & numerical data*
  • Ohio / epidemiology
  • Postoperative Complications / diagnostic imaging
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Surgery, Computer-Assisted / statistics & numerical data*
  • Thrombosis / epidemiology*
  • Tomography, X-Ray Computed / statistics & numerical data*
  • Treatment Outcome