Atopy patch test with Aleuroglyphus ovatus antigen in patients with atopic dermatitis

J Eur Acad Dermatol Venereol. 2015 Jan;29(1):38-41. doi: 10.1111/jdv.12429. Epub 2014 Mar 13.

Abstract

Background: Epicutaneous test made with dust mite antigens.

Objective: Evaluation of the response of the epicutaneous test with Aleuroglyphus ovatus antigen in atopic patients.

Methods: We patch tested 119 individuals, 48 with atopic dermatitis, 50 with respiratory allergy and 21 healthy controls. We compare the positive response frequency to a closed patch test using Aleuroglyphus ovatus antigen in different concentrations and 48 and 96h reading times among those individuals.

Results: Six patients with atopic dermatitis (12.5%) and 4 with respiratory atopy (8.0%) had positive reactions. None of the non-atopic controls had a positive response. As the antigen concentration raised, the number of positive reactions to epicutaneous test raised as well.

Conclusion: Our data suggest a positive relation between Atopy Patch Test positive responses and Aleuroglyphus ovatus antigen concentration, no matter the kind of the atopic clinical expression.

MeSH terms

  • Acaridae / immunology*
  • Adolescent
  • Adult
  • Animals
  • Antigens / administration & dosage
  • Antigens / immunology
  • Case-Control Studies
  • Child
  • Child, Preschool
  • Dermatitis, Atopic / immunology*
  • Female
  • Humans
  • Male
  • Patch Tests
  • Respiratory Hypersensitivity / immunology*
  • Young Adult

Substances

  • Antigens