Druggability of the inward rectifier family: a hope for rare channelopathies?

Future Med Chem. 2014 Jun;6(9):971-3. doi: 10.4155/fmc.14.12. Epub 2014 Feb 18.
No abstract available

Keywords: arrhythmia; gating; heart; helix-bundle crossing; hypertension; hypotension; kidney; nephron; rare diseases; trafficking.

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Andersen Syndrome / drug therapy*
  • Andersen Syndrome / genetics
  • Andersen Syndrome / metabolism
  • Bartter Syndrome / drug therapy*
  • Bartter Syndrome / genetics
  • Bartter Syndrome / metabolism
  • Channelopathies / drug therapy*
  • Channelopathies / genetics
  • Channelopathies / metabolism
  • Humans
  • Molecular Targeted Therapy / trends*
  • Mutation
  • Potassium Channels, Inwardly Rectifying / genetics
  • Potassium Channels, Inwardly Rectifying / metabolism*

Substances

  • Potassium Channels, Inwardly Rectifying