Tracking gene and cell fate for therapeutic gain

Nigel G Kooreman; Julia D Ransohoff; Joseph C Wu

doi:10.1038/nmat3868

Tracking gene and cell fate for therapeutic gain

Nat Mater. 2014 Feb;13(2):106-9. doi: 10.1038/nmat3868.

Authors

Nigel G Kooreman¹, Julia D Ransohoff¹, Joseph C Wu²

Affiliations

¹ 1] Stanford Cardiovascular Institute, 265 Campus Drive, Room G1120B, Stanford, California 94305-5454, USA [2] Departments of Medicine and Radiology (Molecular Imaging Program), 265 Campus Drive, Room G1120B, Stanford, California 94305-5454, USA.
² 1] Stanford Cardiovascular Institute, 265 Campus Drive, Room G1120B, Stanford, California 94305-5454, USA [2] Departments of Medicine and Radiology (Molecular Imaging Program), 265 Campus Drive, Room G1120B, Stanford, California 94305-5454, USA [3] Institute of Stem Cell Biology and Regenerative Medicine, 265 Campus Drive, Room G1120B, Stanford, California 94305-5454, USA.

Abstract

Parallel advances in molecular imaging modalities and in gene- and cell-based therapeutics have significantly advanced their respective fields. Here we discuss how the collaborative, preclinical intersection of these technologies will facilitate more informed and effective clinical translation of relevant therapies.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Review

MeSH terms

Animals
Cell Tracking / methods*
Cell Transplantation / methods*
Gene Expression Profiling / methods*
Genetic Therapy / methods*
Humans
Molecular Imaging / methods*
Treatment Outcome

Abstract

Publication types

MeSH terms

Grants and funding