A rhodamine-appended water-soluble conjugated polymer: an efficient ratiometric fluorescence sensing platform for intracellular metal-ion probing

Chem Commun (Camb). 2014 Feb 25;50(16):2040-2. doi: 10.1039/c3cc48649d.

Abstract

Thewater-soluble CP was conjugatedwith a rhodamine spirolactam for the first time to develop a new FRET-based ratiometric fluorescence sensing platform(CP 1) for intracellular metal-ion probing. CP 1 exhibits excellent water-solubility with twowell-resolved emission peaks, which benefit ratiometric intracellular imaging applications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Ferric Compounds / analysis*
  • Fluorescence Resonance Energy Transfer
  • Fluorescence*
  • Fluorescent Dyes / chemical synthesis
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Ions / analysis
  • Lactams / chemistry*
  • Molecular Structure
  • Polymers / chemistry*
  • Rhodamines / chemistry*
  • Solubility
  • Spiro Compounds / chemistry
  • Water / chemistry

Substances

  • Ferric Compounds
  • Fluorescent Dyes
  • Ions
  • Lactams
  • Polymers
  • Rhodamines
  • Spiro Compounds
  • Water