Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines

Stroke. 2014 Feb;45(2):357. doi: 10.1161/STROKEAHA.113.004148. Epub 2014 Jan 9.

Authors

Johannes Boltze¹, Cenk Ayata, Daniel-Christoph Wagner, Nikolaus Plesnila

Affiliation

¹ From the Fraunhofer Institute of Cell Therapy and Immunology and Translational Center of Regenerative Medicine, University of Leipzig, Leipzig, Germany (J.B., D.-C.W.); Neurovascular Research Laboratory, Departments of Neurology and Radiology, Massachusetts General Hospital and Harvard Medical School, Boston (J.B., C.A.); and Institute for Stroke and Dementia Research, University of Munich Medical Center, Munich, Germany (N.P.).

No abstract available

Keywords: models, animal; quality assurance, healthcare; quality improvement; translational medical research.

MeSH terms

Clinical Trials, Phase III as Topic / trends*
Guidelines as Topic*
Humans
Research Design
Risk Factors
Stroke / physiopathology
Stroke / therapy*
Translational Research, Biomedical / organization & administration*
Translational Research, Biomedical / trends

Grants and funding

P50 NS051343/NS/NINDS NIH HHS/United States