Comparison of surgical completeness between robotic total thyroidectomy versus open thyroidectomy

Laryngoscope. 2014 Apr;124(4):1042-7. doi: 10.1002/lary.24511. Epub 2013 Dec 11.

Abstract

Objectives/hypothesis: The aim of this study was to investigate the surgical completeness of robotic total thyroidectomy compared with conventional open thyroidectomy.

Study design: Retrospective, case-control study.

Methods: We studied 245 patients with papillary thyroid carcinoma who underwent total thyroidectomy and postoperative radioactive iodine (RAI) ablation. Of these, 62 patients underwent robotic thyroidectomy by a gasless unilateral axillo-breast (GUAB) or axillary (GUA) approach, and 183 underwent conventional open thyroidectomy. We analyzed serum TSH-stimulated thyroglobulin (Tg) and RAI uptake at the time of RAI remnant ablation to compare surgical completeness in the two groups.

Results: Tumor characteristics and complications did not differ between the two groups except TNM stage. The mean TSH-stimulated Tg at the first RAI ablation was significantly higher in the robotic group (10.20 ± 9.98 ng/ml) than in the open group (3.85 ± 6.79 ng/ml) (P <0.001). In subgroup analysis of the robotic group by the period in which operations took place, TSH-stimulated Tg was significantly higher than in the open group in the first (13.28 ± 11.91 ng/ml) and second (10.45 ± 9.30 ng/ml) periods, but there was no significant difference in the third period (6.00 ± 6.26 ng/ml, P = 0.141). The RAI uptake rate at the first RAI ablation did not differ between the two groups, and TSH-stimulated Tg after RAI ablation was similar.

Conclusion: The surgical completeness of robotic total thyroidectomy by a GUAB/GUB approach is comparable to that of open thyroidectomy, if performed by experienced robotic thyroid surgeons in properly selected patients.

Level of evidence: 3b. Laryngoscope, 124:1042-1047, 2014.

Keywords: Robotic thyroidectomy; endoscopic thyroidectomy; gasless unilateral axillary approach; gasless unilateral axillo-breast approach; papillary thyroid carcinoma.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Axilla
  • Biomarkers, Tumor / blood
  • Carcinoma / blood
  • Carcinoma / surgery*
  • Carcinoma, Papillary
  • Endoscopy / methods*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Propensity Score
  • Retrospective Studies
  • Robotics / methods*
  • Thyroglobulin / blood*
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / blood
  • Thyroid Neoplasms / surgery*
  • Thyroidectomy / methods*
  • Treatment Outcome

Substances

  • Biomarkers, Tumor
  • Thyroglobulin