Ethnic-specific in vitro-in vivo extrapolation and physiologically based pharmacokinetic approaches to predict cytochrome P450-mediated pharmacokinetics in the Chinese population: opportunities and challenges

Clin Pharmacokinet. 2014 Feb;53(2):197-202. doi: 10.1007/s40262-013-0119-9.

Authors

Guo-Fu Li¹, Guo Yu, Hong-Xia Liu, Qing-Shan Zheng

Affiliation

¹ Center for Drug Clinical Research, Shanghai University of Chinese Medicine, No. 1200 Cailun Road, Shanghai, 201203, China.

PMID: 24255013
DOI: 10.1007/s40262-013-0119-9

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't
Comment

MeSH terms

Asian People*
Cytochrome P-450 Enzyme System / metabolism*
Female
Humans
Male
Models, Biological*
Pharmacokinetics*
White People*

Substances

Cytochrome P-450 Enzyme System