Clinical reasoning: rapidly progressive quadriparesis in a forgetful patient

Neurology. 2013 Nov 19;81(21):e154-8. doi: 10.1212/01.wnl.0000436063.12890.b2.

Abstract

A 50-year-old right-handed retired family business manager developed progressive left-sided weakness over 5 days after a mechanical fall. She remembered catching her foot on the carpet and falling down a flight of stairs, followed by severe neck pain over C4-C5 and inability to get up for nearly an hour. Over the subsequent month her symptoms progressed and she presented to hospital with an asymmetric spastic paraparesis, loss of pinprick sensation in her arms and legs, loss of vibration sense to both hips, and double incontinence.

Publication types

  • Case Reports

MeSH terms

  • Amyotrophic Lateral Sclerosis / complications
  • Amyotrophic Lateral Sclerosis / diagnosis*
  • Amyotrophic Lateral Sclerosis / genetics
  • Diagnosis, Differential
  • Fatal Outcome
  • Female
  • Frontotemporal Dementia / complications
  • Frontotemporal Dementia / diagnosis*
  • Frontotemporal Dementia / genetics
  • Humans
  • Memory Disorders / diagnosis
  • Memory Disorders / etiology
  • Middle Aged
  • Quadriplegia / diagnosis
  • Quadriplegia / etiology