Abstract
Russell-Silver syndrome was reevaluated 2.9 to 13.0 years after initial diagnosis in 15 patients. At follow-up, five of the 15 patients exhibited late catch-up growth and had normal height, six had developmental delays or mental retardation, and asymmetry was present in five. Given the great variability in the long-term prognosis for growth and development in patients with Russell-Silver syndrome, there is a need to reevaluate this syndrome and its clinical implications.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adolescent
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Body Height
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Child
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Child, Preschool
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Developmental Disabilities / diagnosis*
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Developmental Disabilities / physiopathology
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Facial Expression
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Female
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Fetal Growth Retardation / diagnosis
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Follow-Up Studies
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Growth Disorders / diagnosis*
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Growth Disorders / physiopathology
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Humans
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Infant
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Infant, Low Birth Weight
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Infant, Newborn
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Intellectual Disability / diagnosis
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Male
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Pregnancy
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Prognosis
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Psychomotor Disorders / diagnosis
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Psychomotor Disorders / physiopathology
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Sexual Maturation
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Syndrome
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Time Factors