Abstract
The Drug-Gene Interaction database (DGIdb) mines existing resources that generate hypotheses about how mutated genes might be targeted therapeutically or prioritized for drug development. It provides an interface for searching lists of genes against a compendium of drug-gene interactions and potentially 'druggable' genes. DGIdb can be accessed at http://dgidb.org/.
MeSH terms
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Antineoplastic Agents / chemistry
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Breast Neoplasms / drug therapy
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Breast Neoplasms / genetics
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Computational Biology / methods
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Data Mining / methods*
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Databases, Genetic*
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Drug Discovery / methods*
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Drug Interactions
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Gene Expression Regulation / drug effects
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Genetic Variation
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Genome
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Genomics / methods
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Humans
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Lung Neoplasms / drug therapy
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Lung Neoplasms / genetics
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Mutation
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Software
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Technology, Pharmaceutical / methods