Epidemiology of IgE-dependent allergic diseases in elderly patients in Poland

Am J Rhinol Allergy. 2013 Sep-Oct;27(5):e140-5. doi: 10.2500/ajra.2013.27.3920.

Abstract

Background: There is a growing allergy problem in elderly patients. The epidemiology of atopic bronchial asthma (BA), allergic rhinitis, and atopic dermatitis (AD) was analyzed in an elderly Polish population.

Methods: Subject recruitment was conducted at 16 sites representative of Polish rural and urban areas, and 7124 subjects, including 4176 women with a mean age of 67.5 ± 84.9 years and 2948 men with a mean age of 66.1 ± 7.2 years, were screened. Medical examinations, an original questionnaire, skin-prick testing (SPT) with common aeroallergens, and appropriate serum-specific IgE assays were performed.

Results: Suspicion of atopy was diagnosed in 1900 of the 7124 analyzed patients (26.7%), including 1117 women (26.7% of women) and 783 men (26.6% of men). The average morbidity associated with age and sex in this population was 5.9% (95% CI, 5.1-6.4) for BA, 1.6% (95% CI, 15.9-19.3) for AD/eczema, 12.6% (95% CI, 10.8-14.6) for seasonal allergic rhinitis, 17.1% (95% CI, 15.9-19.7) for perennial allergic rhinitis, and 6.4% (95% CI, 5.1-7.3) for polymorphous atopic disease. The most frequent positive results were recorded for the following allergens: mixed grass, Dermatophagoides pteronyssinus, Dermatophagoides farinae, and Alternaria.

Conclusion: This study confirms the high prevalence of allergic rhinitis and BA in elderly Polish patients. These findings are comparable with those involving groups of younger individuals with allergies.

MeSH terms

  • Aged
  • Allergens / immunology
  • Allergens / isolation & purification
  • Asthma / epidemiology*
  • Dermatitis, Atopic / epidemiology*
  • Female
  • Humans
  • Immunoglobulin E / blood
  • Immunoglobulin E / immunology*
  • Male
  • Middle Aged
  • Poland
  • Prevalence
  • Rhinitis, Allergic, Perennial / epidemiology*
  • Rhinitis, Allergic, Seasonal / epidemiology*
  • Rural Population / statistics & numerical data
  • Serologic Tests
  • Skin Tests
  • Urban Population / statistics & numerical data

Substances

  • Allergens
  • Immunoglobulin E