In rare instances, right pneumonectomy can produce progressive exertional dyspnea and reduce ventilatory reserve because of extreme mediastinal shift (right postpneumonectomy syndrome). The diagnosis can be made by bronchoscopy and computed tomography. We report a case of a 43-year-old patient in whom plombage with two Silastic breast implants produced mediastinal derotation and symptomatic relief of this syndrome.