Herbs and liver injury: a clinical perspective

Clin Gastroenterol Hepatol. 2014 Jul;12(7):1069-76. doi: 10.1016/j.cgh.2013.07.030. Epub 2013 Aug 4.

Abstract

Despite a perception that herbal and dietary supplements are safe, devastating liver injury has been reported to result from their use. The difficulty in characterizing liver injury attributable to herbal and dietary supplements stems from the permissive regulatory environment, the complexity of marketed products, and underreporting by the patients who use them. Despite these limitations, researchers, clinicians, and regulators have increasing awareness of the need for study in this area.

Keywords: Causality Assessment in Drug-Induced Liver Injury; Dietary Supplements Induced Liver Injury; Herbal and Induced Liver Injury.

Publication types

  • Review

MeSH terms

  • Dietary Supplements / adverse effects*
  • Hepatic Insufficiency / chemically induced*
  • Humans
  • Plants, Medicinal / adverse effects*