The results of catheterization (transfemoral and transaxial) and embolization of the hepatic artery in 67 patients with malignant hepatic tumors are analysed. In patients with hepatomegaly, the unfavourable topographic-anatomical interrelations of the intraorganic hepatic vessels were established. Distribution of the vessels more accurately is defined by means of ultrasonography. In detection of the unfavourable anatomical factors, the more wide use of primary transaxial catheterization of the hepatic arteries without an attempt of transfemoral catheterization is recommended.