Failure to find association between childhood abuse and cognition in first-episode psychosis patients

L Sideli; H L Fisher; M Russo; R M Murray; S A Stilo; B D R Wiffen; J A O'Connor; M Aurora Falcone; S M Pintore; L Ferraro; A Mule'; D La Barbera; C Morgan; M Di Forti

doi:10.1016/j.eurpsy.2013.02.006

Failure to find association between childhood abuse and cognition in first-episode psychosis patients

Eur Psychiatry. 2014 Jan;29(1):32-5. doi: 10.1016/j.eurpsy.2013.02.006. Epub 2013 Jun 10.

Authors

L Sideli¹, H L Fisher², M Russo³, R M Murray⁴, S A Stilo⁴, B D R Wiffen⁴, J A O'Connor⁴, M Aurora Falcone⁵, S M Pintore⁴, L Ferraro⁶, A Mule'⁶, D La Barbera⁷, C Morgan⁴, M Di Forti⁴

Affiliations

¹ Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK; Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy. Electronic address: lucia.sideli@gmail.com.
² MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK.
³ Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK; Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA.
⁴ Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK.
⁵ Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK; Department of Psychology, Institute of Psychiatry, King's College London, London, UK.
⁶ Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK; Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy.
⁷ Department of Experimental Biomedicine and Clinical Neuroscience, University of Palermo, Palermo, Italy.

PMID: 23764407
DOI: 10.1016/j.eurpsy.2013.02.006

Abstract

This study investigated the relationship between severe childhood abuse and cognitive functions in first-episode psychosis patients and geographically-matched controls. Reports of any abuse were associated with lower scores in the executive function domain in the control group. However, in contrast with our hypothesis, no relationships were found amongst cases.

Keywords: Child abuse; Schizophrenia and psychosis; Social and cross-cultural psychiatry.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Aged
Case-Control Studies
Child
Child Abuse / psychology*
Cognition Disorders / etiology
Cognition Disorders / physiopathology*
Executive Function / physiology*
Female
Humans
Male
Middle Aged
Psychotic Disorders / physiopathology*
Young Adult

Grants and funding

G1002366/MRC_/Medical Research Council/United Kingdom