Septic shock caused by Klebsiella pneumoniae carbapenemase-producing Enterobacter gergoviae in a neutropenic patient with leukemia

J Clin Microbiol. 2013 Aug;51(8):2794-6. doi: 10.1128/JCM.00004-13. Epub 2013 Jun 12.

Abstract

We present the first reported infection caused by Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacter gergoviae. The patient had leukemia and neutropenia and died of septic shock from KPC-producing E. gergoviae bacteremia. The emergence of KPCs in additional species of Enterobacteriaceae is alarming and may disproportionately affect patients with hematologic malignancies.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anti-Bacterial Agents / pharmacology
  • Bacterial Proteins / metabolism*
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification*
  • Enterobacteriaceae Infections / complications
  • Enterobacteriaceae Infections / diagnosis*
  • Enterobacteriaceae Infections / microbiology
  • Enterobacteriaceae Infections / pathology
  • Fatal Outcome
  • Humans
  • Leukemia / complications*
  • Male
  • Microbial Sensitivity Tests
  • Neutropenia / complications*
  • Shock, Septic / complications
  • Shock, Septic / diagnosis*
  • Shock, Septic / microbiology
  • Shock, Septic / pathology
  • beta-Lactamases / metabolism*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • beta-Lactamases
  • carbapenemase