Application of a cognitive neuroscience perspective of cognitive control to late-life anxiety

J Anxiety Disord. 2013 Aug;27(6):559-66. doi: 10.1016/j.janxdis.2013.03.006. Epub 2013 Mar 22.

Abstract

Recent evidence supports a negative association between anxiety and cognitive control. Given age-related reductions in some cognitive abilities and the relation of late life anxiety to cognitive impairment, this negative association may be particularly relevant to older adults. This critical review conceptualizes anxiety and cognitive control from cognitive neuroscience and cognitive aging theoretical perspectives and evaluates the methodological approaches and measures used to assess cognitive control. Consistent with behavioral investigations of young adults, the studies reviewed implicate specific and potentially negative effects of anxiety on cognitive control processes in older adults. Hypotheses regarding the role of both aging and anxiety on cognitive control, the bi-directionality between anxiety and cognitive control, and the potential for specific symptoms of anxiety (particularly worry) to mediate this association, are specified and discussed.

Keywords: Cognitive control; Inhibition; Late-life anxiety; Older adults; Worry.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Aging
  • Anxiety / complications
  • Anxiety / physiopathology*
  • Anxiety / psychology
  • Cognition / physiology*
  • Cognition Disorders / complications
  • Cognition Disorders / physiopathology*
  • Cognition Disorders / psychology
  • Humans
  • Inhibition, Psychological*
  • Neuropsychological Tests
  • Neurosciences