Epidemiology of severe influenza outcomes among adult patients with obesity in Detroit, Michigan, 2011

Influenza Other Respir Viruses. 2013 Nov;7(6):1004-7. doi: 10.1111/irv.12115. Epub 2013 Apr 18.

Abstract

We conducted a retrospective cohort study to evaluate the impact of obesity on influenza disease severity. Individuals with obesity were more likely to have lower pulmonary disease manifestations [OR=1·97 (95% CI 1·05, 3·69), P=0·03] and to be admitted to an inpatient ward [OR=2·93 (95% CI 1·50, 5·71), P=0·002] when compared with non-obese individuals. Among admitted individuals, persons with obesity were more likely to require a lengthy hospital stay [OR=3·86 (95% CI 1·03, 14·42), P=0·045]. Five of the six deaths in study subjects occurred in persons with obesity.

Keywords: Body mass index; influenza - human; obesity.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Cohort Studies
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Influenza, Human / epidemiology*
  • Influenza, Human / mortality
  • Influenza, Human / pathology*
  • Length of Stay
  • Male
  • Michigan / epidemiology
  • Middle Aged
  • Obesity / complications*
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / mortality
  • Pneumonia, Viral / pathology
  • Retrospective Studies
  • Survival Analysis
  • Treatment Outcome